Hi - Is it possible to do CRUD operation of policies using API? Especially update and delete policies

Assuming you are storing your policies in a database (using the sqlite3, mysql, or postgres storage drivers), then yes: https://docs.cerbos.dev/cerbos/latest/api/admin_api.html You can't delete policies, but you can disable them which has the same effect.

Yes we are using mysql

Cool, then you'll just need to enable the admin API in your Cerbos server config. Are you using the Go SDK? It has an AdminClient to handle the API interactions.

yes using Go SDK